๐ง๐๐ ๐๐ฌ๐ฃ๐ข๐ง๐๐๐๐ ๐๐ ๐ฃ๐๐ง๐จ๐๐ง๐๐ฅ๐ฌ ๐๐๐ฅ๐๐ก๐๐ (๐๐ฃ๐) ๐๐ซ๐๐ฆ
- Fendo UK
- Mar 12, 2024
- 2 min read

The Hypothalamic Pituitary Adrenal (HPA) Axis is a crucial neuroendocrine system involved in the body's stress response.
During violent confrontations, the HPA axis plays a significant role in preparing the body to respond to perceived threats and danger.
Here's how the HPA axis functions in relation to violent confrontations......
๐ฃ๐ฒ๐ฟ๐ฐ๐ฒ๐ฝ๐๐ถ๐ผ๐ป ๐ผ๐ณ ๐ง๐ต๐ฟ๐ฒ๐ฎ๐.........When you perceive a threat or experience fear during a violent confrontation, the hypothalamus, (a region of the brain), detects this threat and activates the HPA axis.
๐ฅ๐ฒ๐น๐ฒ๐ฎ๐๐ฒ ๐ผ๐ณ ๐๐ผ๐ฟ๐๐ถ๐ฐ๐ผ๐๐ฟ๐ผ๐ฝ๐ถ๐ป ๐ฅ๐ฒ๐น๐ฒ๐ฎ๐๐ถ๐ป๐ด ๐๐ผ๐ฟ๐บ๐ผ๐ป๐ฒ (๐๐ฅ๐).............The hypothalamus releases corticotropin releasing hormone (CRH) in response to the perceived threat. CRH acts on the anterior pituitary gland, stimulating it to produce adrenocorticotropic hormone (ACTH).
๐ฅ๐ฒ๐น๐ฒ๐ฎ๐๐ฒ ๐ผ๐ณ ๐๐ฑ๐ฟ๐ฒ๐ป๐ผ๐ฐ๐ผ๐ฟ๐๐ถ๐ฐ๐ผ๐๐ฟ๐ผ๐ฝ๐ถ๐ฐ ๐๐ผ๐ฟ๐บ๐ผ๐ป๐ฒ (๐๐๐ง๐)............ACTH is released into the bloodstream and travels to the adrenal glands, which are located on top of the kidneys. ACTH stimulates the adrenal glands to produce and release cortisol, the primary stress hormone.
๐ฅ๐ฒ๐น๐ฒ๐ฎ๐๐ฒ ๐ผ๐ณ ๐๐ผ๐ฟ๐๐ถ๐๐ผ๐น..........Cortisol is released into the bloodstream and exerts a wide range of effects on the body in response to stress. It increases heart rate, blood pressure, and blood sugar levels, providing the body with the energy and resources needed to respond to the threat.
๐ ๐ผ๐ฏ๐ถ๐น๐ถ๐๐ฎ๐๐ถ๐ผ๐ป ๐ผ๐ณ ๐ฅ๐ฒ๐๐ผ๐๐ฟ๐ฐ๐ฒ๐..........Cortisol mobilises energy stores, such as glucose and fatty acids, from tissues like the liver and adipose tissue, making them available for immediate use by muscles and other organs involved in the stress response.
๐ฆ๐๐ฝ๐ฝ๐ฟ๐ฒ๐๐๐ถ๐ผ๐ป ๐ผ๐ณ ๐ก๐ผ๐ป ๐๐๐๐ฒ๐ป๐๐ถ๐ฎ๐น ๐๐๐ป๐ฐ๐๐ถ๐ผ๐ป๐..........Cortisol suppresses non-essential bodily functions that are not immediately necessary for survival during a violent confrontation. These may include digestion, bladder, and immune function.
๐๐ป๐ต๐ฎ๐ป๐ฐ๐ฒ๐ฑ ๐๐ผ๐ด๐ป๐ถ๐๐ถ๐๐ฒ ๐๐๐ป๐ฐ๐๐ถ๐ผ๐ป..........Cortisol enhances cognitive function and alertness, allowing you to focus attention, make quick decisions, and respond effectively to the threat.
๐ฅ๐ฒ๐ด๐๐น๐ฎ๐๐ถ๐ผ๐ป ๐ผ๐ณ ๐๐บ๐ผ๐๐ถ๐ผ๐ป๐ฎ๐น ๐ฅ๐ฒ๐๐ฝ๐ผ๐ป๐๐ฒ๐..........Cortisol modulates emotional responses to stress, helping you regulate fear, anxiety, and aggression during violent confrontations.
๐ง๐ฒ๐ฟ๐บ๐ถ๐ป๐ฎ๐๐ถ๐ผ๐ป ๐ผ๐ณ ๐ฆ๐๐ฟ๐ฒ๐๐ ๐ฅ๐ฒ๐๐ฝ๐ผ๐ป๐๐ฒ..........
Once the threat has been resolved or removed, cortisol levels begin to decline, and the stress response is gradually terminated. This allows the body to return to its baseline state of physiological functioning.
In summary, the HPA axis plays a vital role in preparing the body to respond to violent confrontations by mobilising energy resources, enhancing cognitive function, and regulating emotional responses to stress. Understanding the functioning of the HPA axis can provide insights into the physiological mechanisms underlying the body's response to threatening situations and inform strategies for managing stress and promoting resilience in high pressure environments.
DJN
Fendo UK